General Information

  • ID:  hor002741
  • Uniprot ID:  E9GIT4
  • Protein name:  CCHamide
  • Gene name:  NA
  • Organism:  Daphnia pulex (Water flea)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0005184 neuropeptide hormone activity
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005615 extracellular space

Sequence Information

  • Sequence:  NCNKYGNACFGAH
  • Length:  13(20-32)
  • Propeptide:  MHIFFYVIHVTAMLAIVSGNCNKYGNACFGAHGKRSDFKRTSAVDLSDQIWPVAANWNPTRPDEPIQERRQMKPLPALQLESVLVYNDIPRSAEHSRYLNQEDYNN
  • Signal peptide:  MHIFFYVIHVTAMLAIVSG
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9GIT4-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002741_AF2.pdbhor002741_ESM.pdb

Physical Information

Mass: 161277 Formula: C58H83N19O18S2
Absent amino acids: DEILMPQRSTVW Common amino acids: N
pI: 8.23 Basic residues: 2
Polar residues: 8 Hydrophobic residues: 3
Hydrophobicity: -63.85 Boman Index: -1923
Half-Life: 1.4 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 15.38
Instability Index: 3290.77 Extinction Coefficient cystines: 1615
Absorbance 280nm: 134.58

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones